Transcriptional Regulation of CDR1, a major efflux pump involved in multidrug resistance in Candida albicans

Candida albicans apart from being the most common human fungal pathogen is also the omnipresent component of the mammalian micro biome. In recent years, the incidence of fungal infection has shown a remarkable increase. Candida albicans, is one of the major fungus which is found to be responsible for skin infections (Morrison et al, 2006). Candida albicans exists as a commensal organism in healthy individuals but becomes pathogenic in immune compromised individuals. In United States, Candidiasis causes fourth most common nosocomial bloodstream infection.